U.S. 501 begins in Myrtle Beach, South Carolina. U.S. 15/501 combine in Laurinburg and commingle for two thirds of their course in North Carolina northward to Pinehurst, Sanford, Pittsboro and Durham. Coming into Chapel Hill along a four lane highway north from U.S. 64 on the Pittsboro bypass, U.S. 15-501 bring a fair amount of traffic into the Triangle region. Through Chapel Hill, U.S. 15/501 (Fordham Boulevard) bypass the city center and the University of North Carolina along an arterial bypass. The former old alignment enters Downtown along NC 86 and E Franklin Street.
Beyond Durham, U.S. 15 generally follows I-85 northeast to Oxford, then turns north toward Virginia. U.S. 501 traces a route north to Roxboro and South Boston, Virginia, before turning northwest toward Lynchburg and Buena Vista, where it ends.
U.S. 501 North Carolina Guides
- U.S. 15/501 North - Chapel Hill to Durham
- U.S. 15/501 South - Durham to Chapel Hill
- U.S. 15/501 South - Carthage to Laurinburg
 South |
 | U.S. 501 combines with U.S. 301 southwest from NC 130 (Main Street) in Rowland 2.67 miles to the South Carolina state line at South of the Border. 12/28/22 |
Photo Credits:
12/28/22 by AARoads
Connect with:
Interstate 40
Interstate 74
Interstate 85
U.S. 15
U.S. 64
U.S. 70
U.S. 401
Page Updated 01-16-2023.